LITTLE KNOWN FACTS ABOUT BET 138.

Hemoglobin Brockton [beta 138 (H16) Ala—-Pro] has reduced oxygen affinity but electrophoretic mobility and hemolysate binding are regular, suggesting that the substitution at beta 138 will not disrupt critical polar interactions, like the hydrogen bonds and salt bridges involving Asp 137 and Professional 138, that lead on the cooperative oxygen-b